Take control of your skincare routine with Differin Gel, the first FDA-approved, prescription-strength retinoid available over the counter to clear and prevent acne. Unlike traditional acne treatments, Differin works at the source by normalizing skin cell turnover and targeting two major causes of acne—clogged pores and inflammation—for more effective, long-term results.

Formulated with Adapalene, a retinoid known for its superior tolerability, Differin is ideal for both morning and evening routines. The water-based, oil-free, and non-comedogenic formula is dermatologist-recommended and helps reduce the risk of scarring and hyperpigmentation. In clinical studies, users saw up to an 87% reduction in breakouts after 12 weeks, with continued improvement over time. Clearer skin starts here.

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